modular organic synthesis

Modular Total Synthesis of Archazolid A and B | The ...

A modular total synthesis of the potent V-ATPase inhibitors archazolid A and B is reported. The convergent preparation was accomplished by late-stage diversification of joint intermediates. Key synthetic steps involve asymmetric boron-mediated aldol reactions, two consecutive Still−Gennari olefinations to set the characteristic (Z,Z)-diene system, a Brown crotyboration, and a ...

Organic synthesis in a modular robotic system driven by a ...

Jan 11, 2019· The Chemputer allows for an abstraction of chemical synthesis, when coupled with a high-level chemical programming language, to be compiled by our Chempiler into a low-level code that can run on a modular standard robotic platform for organic synthesis. The software and modular hardware standards permit synthetic protocols to be captured as ...

Pittsburgh Modular Synthesizers

May 08, 2019· The Microvolt 3900 merges a unique analog synthesis engine with beautiful design and the creative freedom of a modular synthesizer to define the desktop sonic laboratory. The sound of the Microvolt 3900 is a unique blend of the organic and textural with raw, synthetic analog tones creating a new sonic palate perfect for deep experimentation.

‎Factory - Modular Synthesizer on the App Store

Made for complex and organic sounds, Factory sports a big modulation matrix with all kinds of features to create a wildlife of sounds. A vast array of DSP is ready to play: Analog style oscillators and filters, but also different flavors of wavetable synthesis, Wavetable driven Waveguide resonators and a 3-FX-Chain in a dynamic signal flow.

Organic synthesis toward small-molecule probes and drugs

organic synthesis and related disciplines. The contributions highlight short and modular syntheses of structural variants of natural products having novel proper-ties as probes and drugs. They also de-scribe modular syntheses of compounds both poised for optimization and having stereochemical complexity and skeletal diversity. They describe ...

Modular, stereocontrolled Cβ–H/Cα–C activation of alkyl ...

Apr 30, 2019· The combination of two newly emerging methods for chemical synthesis enables access to molecular space that was previously challenging or impossible to access. Thus, a C–H activation of ubiquitous carboxylic acids followed by their decarboxylative functionalization provides modular access to difunctionalized carbon frameworks with distinctly controlled stereochemistry.

Synthesis of Modular "Inorganic–Organic–Inorganic ...

Yan Bai, Guo-Qiang Zhang, Dong-Bin Dang, Peng-Tao Ma, Hui Gao and Jing-Yang Niu, Assembly of polyoxometalate-based inorganic–organic compounds from silver–Schiff base building blocks: synthesis, crystal structures and luminescent properties, …

Multistep organic synthesis of modular photosystems

Synthesis of initiators. Photosystem 1 is constructed from the molecular building blocks 2–6 (Schemes 1-3). Initiator 2 is composed of a central naphthalenediimide (NDI) [4–19] to act as a template for the central stack and two peripheral NDIs to act as templates for stack exchange.They are embedded into hydrogen-bonded networks, to assure self-organization, and four geminal diphosphonates ...

Multistep organic synthesis of modular photosystems

Feb 18, 2012· Multistep organic synthesis of modular photosystems. Quite extensive synthetic achievements vanish in the online supporting information of publications on functional systems. Underappreciated, their value is recognized by experts only. As an example, we here focus in on the recent synthesis of multicomponent photosystems with antiparallel ...

(PDF) Multistep organic synthesis of modular photosystems

Multistep organic synthesis of modular photosystems Article (PDF Available) in Beilstein Journal of Organic Chemistry 8(1):897-904 · June 2012 with 17 Reads How we measure 'reads'

Voltage Research Laboratory organic modular synthesizer ...

May 09, 2019· The Voltage Research Laboratory based in Pittsburgh has created an organic modular synthesiser designed to help musicians and music makers …

Modular and Stepwise Synthesis of a Hybrid Metal–Organic ...

The paddle-wheel type cluster Co2(RCOO)4(LT)2 (R = substituent group, LT = terminal ligand), possessing unusual metal coordination geometry compared with other cobalt compounds, may display high catalytic activity but is highly unstable especially in water. Here, we show that with judicious considerations of the host/guest geometries and modular synthetic strategies, the labile dicobalt ...

Porous organic cages: soluble, modular and molecular pores ...

Jul 26, 2016· In this Review, the synthesis and structures of various porous organic cages are outlined together with a discussion of the characteristics — such as solubility, polymorphism and modular co ...

Organic synthesis in a modular robotic system driven by a ...

We recently showed a modular platform for automating batch organic synthesis, which embodies our abstraction in 'the Chemputer' (Figure 4) [1]. Our abstraction of organic synthesis ( Figure 4A ...

Modular Synthesis of Bifunctional Linkers for Materials ...

A practical synthesis of α,ω‐bifunctional linkers is described that is based on three building blocks, namely, thioctic acid, a spacer‐arm of seven ethylene glycol units, and a functional motif dedicated to the selective immobilization of purposely tagged proteins.

ORGANIC SYNTHESIS - UGent Chemtech

– The concepts of versatile ligation reactions and modular building blocks in organic synthesis are also explored and applied in various collabora-tive research projects going from macromolecular and materials science to chemical biology. The Organic and Biomimetic Chemistry Research Group is

Organic synthesis toward small-molecule probes and drugs ...

Apr 26, 2011· Organic Synthesis of Small-Molecule Probes and Drugs. Chemists and biologists have been exploring the functions of small molecules in living systems for over a century, beginning with the discovery of glucose, amino acids, vitamins, hormones, neurotransmitters, lipid …

(PDF) Modular Organic Structure-Directing Agents for the ...

PDF | Organic structure-directing agents (OSDAs) are used to guide the formation of particular types of pores and channels during the synthesis of zeolites. We report that the use of highly ...

Modular synthesizer - Wikipedia

The modular synthesizer is a type of synthesizer, which exists in both physical and virtual forms, consisting of separate specialized modules. The modules are not hardwired together by the manufacturer but can be connected together with patch cords, a matrix patching system, or switches by the user to …

Modular synthesis and immunological evaluation of ...

Organic & Biomolecular Chemistry; ... Herein, we report the chemical synthesis of a suspected allergen 4PX and three closely related oligosaccharides based on a modular approach. The fact that synthesized 4PX and a regioisomer did not cause basophil activation in subjects with confirmed GOS-allergy excludes both tetrasaccharides as key-epitopes ...

Organic Building Blocks - Alfa Chemistry

Organic building block is a term in organic chemistry, which is used to describe an organic compound with functional groups. Organic building blocks are mainly used for bottom-up modular assembly of metal-organic frameworks, organic molecular constructs, and supra-molecular complexes.

volca modular - MICRO MODULAR SYNTHESIZER | KORG (USA)

A semi-modular analog synthesizer that makes modular synthesis more accessible and understandable than ever before. Creating new sounds that don't exist in the outside world is an unending dream which has continued since the birth of electronic musical instruments.

Modular synthesis of heptaarylindole - Organic ...

The first synthesis of heptaarylindole (HAI) has been accomplished using a coupling/ring transformation strategy. Four readily prepared modular units (diarylthiophenes, 2-arylaziridines, arylboronic acids, and arylalkynes) were joined together to provide key ynamide intermediates. Subsequent inverse electron

Modular Synthesis of Amine-Functionalized Oxazolines ...

The Journal of Organic Chemistry 2008, 73 (11), 4320-4322. DOI: 10.1021/jo8003937. Jeremie J. Miller and, Matthew S. Sigman. Design and Synthesis of Modular Oxazoline Ligands for the Enantioselective Chromium-Catalyzed Addition of Allyl Bromide to Ketones.

Voltage Research Laboratory Organic Modular Synthesizer by ...

An Organic Synthesizer by Pittsburgh Modular. The Voltage Research Laboratory is a completely different analog synthesizer where every function of the instrument has been influenced by the behaviors and systems of the natural world.

Modularity: Adding New Dimensions to Total Synthesis ...

Jun 20, 2019· As the field of synthetic chemistry seeks to tackle new frontiers, total synthesis is primed to address significant medical challenges such as the rise of antibiotic resistance and cancer. One emerging frontier focuses on increasingly concerted efforts to utilize modular total synthesis as a strategy to generate analogs of natural product targets for biological studies, with the ultimate goal ...

Modularity: Adding New Dimensions to Total Synthesis ...

Thus, the practice of modular synthesis seeks to push the field to new heights through utilizing chemical ingenuity to identify and execute modular routes to natural products. Ultimately, one goal of modular synthesis is to identify lead-like compounds that may be developed into new medicines.

Voltage Research Laboratory Organic Modular Synthesizer ...

May 10, 2019· An Organic Synthesizer by Pittsburgh Modular The Voltage Research Laboratory is a completely different analog synthesizer where every function of the instrument has been influenced by the ...

About - kickstarter.com

An Organic Synthesizer by Pittsburgh Modular. The Voltage Research Laboratory is a completely different analog synthesizer where every function of the instrument has been influenced by the behaviors and systems of the natural world.